Human Estradiol 17-beta-dehydrogenase 8, HSD17B8 ELISA Kit

SKU: E3327Hu

Size:96 Tests-1 Kit

Background:NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone (PubMed: 17978863). The heterotetramer with CBR4 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis (PubMed: 19571038, PubMed: 25203508). Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD (PubMed: 25203508).

Research_area:Signal Transduction

Applications:ELISA

Target_protein:HSD17B8

Reactivity:Human

Assay type:Sandwich

Sensitivity:12.09ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Estradiol 17-Beta-Dehydrogenase 8

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q92506

MASS(Da):26,974

GeneID:7923

Synonyms:17-beta-HSD 8;17-beta-hydroxysteroid dehydrogenase 8;3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit;3-oxoacyl-[acyl-carrier-protein] reductase;Estradiol 17-beta-dehydrogenase 8;HSD17B8;KAR alpha subunit;Ke-6;Protein Ke6;Really interesting new gene 2 protein;Short chain dehydrogenase/reductase family 30C member 1;Testosterone 17-beta-dehydrogenase 8

Gene names:HSD17B8

Standard solution:4800ng/L