Human EDAR ELISA Kit PicoKine®

SKU: EK1851

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: EDAR

Specificity: Natural and recombinant human EDAR

Background: Ectodysplasin A receptor (EDAR) is a protein that in humans is encoded by the EDAR gene. It is mapped to 2q13. This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: E27-A187

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Reference:

Uniprot ID: Q9UNE0

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 10913

Protein Name: Tumor necrosis factor receptor superfamily member EDAR

Gene Full Name: ectodysplasin A receptor

Synonyms: DL; Downless homolog; Ectodermal dysplasia receptor; ectodysplasin A receptor; ED1R; ED3; ED5; EDA A1 receptor; EDA A1R; EDA1R; EDA3; EDAR; HRM1