Human Ectonucleoside Triphosphate Diphosphohydrolase 4, ENTPD4 ELISA Kit

SKU: E5223Hu

Size:96 Tests-1 Kit

Background:Catalyzes the hydrolysis of nucleoside triphosphates and diphosphates in a calcium- or magnesium-dependent manner, with a preference for pyrimidines. Preferentially hydrolyzes UTP and TTP. AMP, ADP, ATP and UMP are not substrates (PubMed:10858452, PubMed:9556635). Preferentially activated by Ca2+ over Mg2+ (PubMed:10858452). Has a broad substrate specificity with the ability of cleaving all nucleotide di- and triphosphates with the exception of adenosine di- and triphosphate (ADP and ATP). Preferentially hydrolyzes CTP, UDP, CDP, GTP and GDP. Can use either Ca2+ or Mg2+ equally.

Research_area:Epigenetics and Nuclear Signaling

Applications:ELISA

Target_protein:ENTPD4

Reactivity:Human

Assay type:Sandwich

Sensitivity:4.65ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Ectonucleoside triphosphate diphosphohydrolase 4

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9Y227

MASS(Da):70,255

GeneID:9583

Synonyms:Ectonucleoside triphosphate diphosphohydrolase 4;ENTPD4;Golgi UDPase;LALP70;LAP70;LYSAL1;Lysosomal apyrase-like protein of 70 kDa;NTPDase 4;NTPDase-4;UDPase;Uridine-diphosphatase

Gene names:ENTPD4

Standard solution:2400ng/L