Human DCR3/TNFRSF6B ELISA Kit PicoKine®

SKU: EK0748

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: TNFRSF6B

Specificity: Natural and recombinant human DCR3

Background: Decoy receptor 3 (Dcr3), also known as tumor necrosis factor receptor superfamily member 6B (TNFRSF6B), TR6 and M68, is a soluble protein of the tumor necrosis factor receptor superfamily which inhibits Fas ligand-inducedapoptosis. This gene belongs to the tumor necrosis factor receptor superfamily. It acts as a decoy receptor that competes with death receptors for ligand binding. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death and T cell activation as well as to induce angiogenesis via neutralization of TL1A. Overexpression of this gene has been noted in various tumors e.g. gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes.

Immunogen: Expression system for standard: NS0; Immunogen sequence: V24-H300

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Reference:

Uniprot ID: O95407

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Cross Reactivity: No cross reactivity with other proteins.

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Gene ID: 8771

Protein Name: Tumor necrosis factor receptor superfamily member 6B

Gene Full Name: TNF receptor superfamily member 6b

Synonyms: TNFRSF6B; M68; TR6; DCR3; M68E; DJ583P15.1.1; UNQ186/PRO212; Tumor necrosis factor receptor superfamily member 6B; Decoy receptor 3; DcR3