Human Cystathionine Beta-synthase, CBS ELISA Kit

SKU: E3445Hu

Size:96 Tests-1 Kit

Background:Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine (PubMed: 23981774, PubMed: 20506325, PubMed: 23974653). Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons (By similarity).

Research_area:Metabolism

Applications:ELISA

Target_protein:CBS

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.027ng/ml

Detection range:0.05-20ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Cystathionine Beta-Synthase

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P35520

MASS(Da):60,587

GeneID:102724560875

Synonyms:Beta-thionase;CBS;Cystathionine beta-synthase;Serine sulfhydrase

Gene names:CBS

Standard solution:24ng/ml