Human Cyclin T1, CCNT1 ELISA Kit

SKU: E2283Hu

Size:96 Tests-1 Kit

Background:Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to productive elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNA Pol II). (Microbial infection) In case of HIV or SIV infections, binds to the transactivation domain of the viral nuclear transcriptional activator, Tat, thereby increasing Tat's affinity for the transactivating response RNA element (TAR RNA). Serves as an essential cofactor for Tat, by promoting RNA Pol II activation, allowing transcription of viral genes.

Research_area:Microbiology

Applications:ELISA

Target_protein:CCNT1

Reactivity:Human

Assay type:Sandwich

Sensitivity:4.96ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Cyclin T1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O60563

MASS(Da):80,685

GeneID:904

Synonyms:CCNT 1;CCNT1;Cyclin-T;Cyclin-T1;CycT1

Gene names:CCNT1

Standard solution:2400ng/L