Human Chitinase-3-like Protein 1, CHI3L1 ELISA Kit

SKU: E2063Hu

Size:96 Tests-1 Kit

Background:Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.

Research_area:Signal Transduction

Applications:ELISA

Target_protein:CHI3L1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.61ng/ml

Detection range:1-400ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Chitinase-3-Like Protein 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P36222

MASS(Da):42,625

GeneID:1116

Synonyms:39 kDa synovial protein;Cartilage glycoprotein 39;CGP-39;CHI3L1;Chitinase-3-like protein 1;GP-39;hCGP-39;YKL-40

Gene names:CHI3L1

Standard solution:480ng/ml