Human Chitinase 3-like 1/YKL-40 ELISA Kit PicoKine®

SKU: EK0974

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: CHI3L1

Specificity: Natural and recombinant human Chitinase 3-like 1

Background: Chitinase-3-like protein 1, also called CHI3L1 or YKL-40 is a secreted glycoprotein that is approximately 40kDa in size that in humans is encoded by the CHI3L1 gene. This gene is mapped to 1q32.1. Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling.

Immunogen: Expression system for standard: NS0; Immunogen sequence: Y22-T383

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Reference:

Uniprot ID: P36222

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 1116

Protein Name: Chitinase-3-like protein 1

Gene Full Name: chitinase 3 like 1

Synonyms: 39 kDa synovial protein; ASRT7; Cartilage glycoprotein 39; CGP 39; CHI3L1; CHI3L1/YKL40; Chitinase 3 like protein 1; Chitinase 3-like 1; GP 39; GP39; HC gp39; hCGP 39; HCGP 3P; YKL 40; YKL40; YYL 40