Human Chemokine-like Protein Tafa-5, TAFA5 ELISA Kit

SKU: E6705Hu

Size:96 Tests-1 Kit

Background:Acts as a chemokine-like protein by regulating cell proliferation and migration through activation of G protein-coupled receptors (GPCRs), such as S1PR2 and FPR2 (By similarity). Stimulates chemotactic migration of macrophages mediated by the MAPK3/ERK1 and AKT1 pathway (By similarity). Blocks TNFSF11/RANKL-induced osteoclast formation from macrophages by inhibiting up-regulation of osteoclast fusogenic and differentiation genes (By similarity). Stimulation of macrophage migration and inhibition of osteoclast formation is mediated via GPCR FPR2 (By similarity). Acts as an adipokine by negatively regulating vascular smooth muscle cell (VSMC) proliferation and migration in response to platelet-derived growth factor stimulation via GPCR S1PR2 and G protein GNA12/GNA13-transmitted RHOA signaling (By similarity). Inhibits injury-induced cell proliferation and neointima formation in the femoral arteries (By similarity).

Research_area:Others

Applications:ELISA

Target_protein:TAFA5

Reactivity:Human

Assay type:Sandwich

Sensitivity:10.69ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Chemokine-Like Protein Tafa-5

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q7Z5A7

MASS(Da):14,301

GeneID:25817

Synonyms:Chemokine-like protein TAFA-5;TAFA 5;TAFA5

Gene names:TAFA5

Standard solution:4800ng/L