Human CD51 ELISA Kit PicoKine®

SKU: EK2223

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: ITGAV

Specificity: Natural and recombinant human ITGAV

Background: Integrin alpha-V is a protein that in humans is encoded by the ITGAV gene. The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

Immunogen: Expression system for standard: CHO; Immunogen sequence: F31-V992

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Reconstitution:

Reference:

Uniprot ID: P06756

Host:

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

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Gene ID: 3685

Protein Name: Integrin alpha-V

Gene Full Name: integrin subunit alpha V

Synonyms: CD51; Integrin alpha V; ITGAV; MSK8; VNRA