Human CD42d ELISA Kit PicoKine®

SKU: EK2211

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: GP5

Specificity: Natural and recombinant human GP5

Background: Glycoprotein V (platelet) (GP5) also known as CD42d (Cluster of Differentiation 42d), is a human gene. Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome, a bleeding disorde.

Immunogen: Expression system for standard: NS0; Immunogen sequence: Q17-G560

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Reference:

Uniprot ID: P40197

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 2814

Protein Name: Platelet glycoprotein V

Gene Full Name: glycoprotein V platelet

Synonyms: GP5; Platelet glycoprotein V; GPV; Glycoprotein 5; CD42d