Human CD320 / 8D6A / TCblR ELISA Kit PicoKine®

SKU: EK1255

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: CD320

Specificity: Natural and recombinant human CD320

Background: CD320 (cluster of differentiation 320), also known as 8D6A or TCBLR, is a human gene. It is mapped to chromosome 19p13.2. This gene encodes the transcobalamin receptor that is expressed at the cell surface. It mediates the cellular uptake of transcobalamin bound cobalamin (vitamin B12), and the expression of CD320 enhanced B-cell proliferation and immunoglobulin secretion. Mutations in this gene are associated with methylmalonic aciduria. It has been found that antagonists of the CD320 signaling pathway may counter the growth of follicular lymphomas or other tumors that metastasize to lymphoid follicles. CD320 is also a specific receptor for uptake of TCN2-bound cobalamin.

Immunogen: Expression system for standard: NS0; Immunogen sequence: S36-Y229

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Reconstitution:

Reference:

Uniprot ID: Q9NPF0

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Conjugate:

Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

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Gene ID: 51293

Protein Name: CD320 antigen

Gene Full Name: CD320 molecule

Synonyms: 8D6; 8D6 antigen; 8D6A; CD320; CD320 antigen; CD320 molecule; FDC signaling molecule 8D6; FDC SM 8D6; TCblR; Transcobalamin receptor