Human Carbonic Anhydrase 12, CA12 ELISA Kit

SKU: E3917Hu

Size:96 Tests-1 Kit

Background:Carbonic anhydrase 12 is an enzyme that in humans is encoded by the CA12 gene. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Two transcript variants encoding different isoforms have been identified for this gene.

Research_area:Tags & Cell Markers

Applications:ELISA

Target_protein:CA12

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.022ng/ml

Detection range:0.05-20ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Carbonic Anhydrase 12

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O43570

MASS(Da):39,451

GeneID:771

Synonyms:CA12;Carbonate dehydratase XII;Carbonic anhydrase 12;Carbonic anhydrase XII;CAXII;CA-XII;HsT18816;T18816;Tumor antigen HOM-RCC-3.1.3;

Gene names:CA12

Standard solution:24ng/ml