Human Bone Morphogenetic Protein Receptor 2, BMPR2 ELISA Kit

SKU: E1563Hu

Size:96 Tests-1 Kit

Background:On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.

Research_area:Cardiovascular

Applications:ELISA

Target_protein:BMPR2

Reactivity:Human

Assay type:Sandwich

Sensitivity:1.64ng/L

Detection range:3-900ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Bone Morphogenetic Protein Receptor 2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q13873

MASS(Da):115,201

GeneID:659

Synonyms:BMP type II receptor;BMP type-2 receptor;BMPR 2;BMPR2;BMPR-2;BMPR-II;Bone morphogenetic protein receptor type II;Bone morphogenetic protein receptor type-2

Gene names:BMPR2

Standard solution:960ng/L