Human Atp-sensitive Inward Rectifier Potassium Channel 12, KCNJ12 ELISA Kit

SKU: E1799Hu

Size:96 Tests-1 Kit

Background:Inward rectifying potassium channel that is activated by phosphatidylinositol 4,5-bisphosphate and that probably participates in controlling the resting membrane potential in electrically excitable cells. Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.

Research_area:Others

Applications:ELISA

Target_protein:KCNJ12

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.021ng/ml

Detection range:0.05-20ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:ATP-sensitive inward rectifier potassium Channel 12

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q14500

MASS(Da):49,001

GeneID:3768

Synonyms:ATP-sensitive inward rectifier potassium Channel 12;hIRK;hIRK1;hkir2.2x;Inward rectifier K(+ Channel Kir2.2;Inward rectifier K(+ Channel Kir2.2v;IRK2;IRK-2;KCNJ12;kcnj12x;KCNJN1;Kir2.2;Potassium Channel, inwardly rectifying subfamily J member 12;

Gene names:KCNJ12

Standard solution:24ng/ml