Human Atp-sensitive Inward Rectifier Potassium Channel 11, KCNJ11 ELISA Kit

SKU: E1796Hu

Size:96 Tests-1 Kit

Background:This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium (By similarity). Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with ABCC9. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation.

Research_area:Neuroscience

Applications:ELISA

Target_protein:KCNJ11

Reactivity:Human

Assay type:Sandwich

Sensitivity:8.87ng/L

Detection range:20-6000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:ATP-sensitive inward rectifier potassium Channel 11

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q14654

MASS(Da):43,541

GeneID:3767

Synonyms:ATP-sensitive inward rectifier potassium Channel 11;BIR;HHF2;IKATP;Inward rectifier K(+ Channel Kir6.2;KCNJ11;MODY13;PHHI;PNDM2;Potassium Channel, inwardly rectifying subfamily J member 11;TNDM3

Gene names:KCNJ11

Standard solution:6400ng/L