Human Arylsulfatase A/ARSA ELISA Kit PicoKine®

SKU: EK2077

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: ARSA

Specificity: Natural and recombinant human ARSA

Background: Arylsulfatase A (or cerebroside-sulfatase) is an enzyme that breaks down sulfatides, namely cerebroside 3-sulfate into cerebroside and sulfate. In humans, arylsulfatase A is encoded by the ARSA gene. It is mapped to 22q13.33. The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.

Immunogen: Expression system for standard: NS0; Immunogen sequence: R19-A507

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Reconstitution:

Reference:

Uniprot ID: P15289

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

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Gene ID: 410

Protein Name: Arylsulfatase A

Gene Full Name: arylsulfatase A

Synonyms: ARSA; arylsulfatase A; ASA; Cerebroside sulfatase; MLD