Human ANGPTL2 PicoKine® Quick ELISA Kit

SKU: FEK2039

Size: 96 wells/kit, with removable strips.

Storage: Store at 4°C for 6 months. (Ships with gel ice, can store for up to 3 days in room temperature. Refrigerate upon receipt.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: ANGPTL2

Specificity: Natural and recombinant human ANGPTL2

Background: Angiopoietin-related protein 2 also known as angiopoietin-like protein 2 is a protein that in humans is encoded by the ANGPTL2 gene. This gene is mapped to 9q33.3. Angiopoietin-like protein 2 maintains tissue homeostasis by promoting adaptive inflammation and subsequent tissue reconstruction, whereas an excess of ANGPTL2 activation induced by prolonged stress promotes the breakdown of tissue homeostasis due to chronic inflammation, promoting the development of metabolic diseases. ANGPTL2 has a role also in angiogenesis, in tissue repair, in obesity, in atherosclerotic diseases and finally in carcinogenesis. Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 protein is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action.

Immunogen: Expression system for standard: NS0; Immunogen sequence: Q23-H493

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Reference:

Uniprot ID: Q9UKU9

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 23452

Protein Name: Angiopoietin-related protein 2

Gene Full Name: angiopoietin like 2

Synonyms: angiopoietin like 2; Angiopoietin like protein 2; Angiopoietin related protein 2; ANGPTL2; ARP2; HARP