Human ADAMTS4 ELISA Kit PicoKine®

SKU: EK1372

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: ADAMTS4

Specificity: Natural and recombinant human ADAMTS4

Background: ADAMTS4, A disintegrin and metalloproteinase with thrombospondin motifs 4 is an enzyme that in humans is encoded by the ADAMTS4 gene. ADAMTS4 is a member of the large ADAMTS family of zinc-dependent proteases. The human ADAMTS4 gene is mapped to chromosome 1 by somatic cell hybrid analysis. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.

Immunogen: Expression system for standard: CHO; Immunogen sequence: F213-C685

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Reference:

Uniprot ID: O75173

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 9507

Protein Name: A disintegrin and metalloproteinase with thrombospondin motifs 4

Gene Full Name: ADAM metallopeptidase with thrombospondin type 1 motif 4

Synonyms: ADAM TS 4; ADAM TS4; ADAMTS 2; ADAMTS 4; ADAMTS4; ADMP 1; Aggrecanase 1; KIAA0688