Human A Disintegrin And Metalloprotease 15,ADAM15 ELISA KIT

SKU: E2811Hu

Size:96 Tests-1 Kit

Background:Active metalloproteinase with gelatinolytic and collagenolytic activity. Plays a role in the wound healing process. Mediates both heterotypic intraepithelial cell/T-cell interactions and homotypic T-cell aggregation. Inhibits beta-1 integrin-mediated cell adhesion and migration of airway smooth muscle cells. Suppresses cell motility on or towards fibronectin possibly by driving alpha-v/beta-1 integrin (ITAGV-ITGB1) cell surface expression via ERK1/2 inactivation. Cleaves E-cadherin in response to growth factor deprivation. Plays a role in glomerular cell migration. Plays a role in pathological neovascularization. May play a role in cartilage remodeling. May be proteolytically processed, during sperm epididymal maturation and the acrosome reaction. May play a role in sperm-egg binding through its disintegrin domain. {ECO:0000269|PubMed:12091380, ECO:0000269|PubMed:15358598, ECO:0000269|PubMed:15818704, ECO:0000269|PubMed:17416588, ECO:0000269|PubMed:17575078, ECO:0000269|PubMed:18387333, ECO:0000269|PubMed:18434311}.

Research_area:

Applications:ELISA

Target_protein:ADAM15

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.28ng/ml

Detection range:0.5-200ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:A Disintegrin And Metalloprotease 15

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q13444

MASS(Da):92959

GeneID:8751

Synonyms:ADAM15 MDC15

Gene names:ADAM15

Standard solution:240ng/ml