Human 6-phosphofructo-2-kinase, PFKFB1 ELISA Kit

SKU: E3190Hu

Size:96 Tests-1 Kit

Background:6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene. This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.

Research_area:Signal Transduction

Applications:ELISA

Target_protein:PFKFB1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.022ng/ml

Detection range:0.05-20ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P16118

MASS(Da):54,681

GeneID:5207

Synonyms:6PF-2-K/Fru-2,6-P2ase 1;6PF-2-K/Fru-2,6-P2ase liver isozyme [Includes: 6-phosphofructo-2-kinase;6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1;F6PK;Fructose-2,6-bisphosphatase;HL2K;PFK/FBPase 1;PFKFB1;PFRX;

Gene names:PFKFB1

Standard solution:24ng/ml