Human 3-hydroxy-3-methylglutaryl-coenzyme A Synthase 1, HMGCS1 ELISA Kit

SKU: E0957Hu

Size:96 Tests-1 Kit

Background:Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis (PubMed:2991281, PubMed:21357570, PubMed:6995544). HMGCR is the main target of statins, a class of cholesterol-lowering drugs (PubMed:11349148, PubMed:18540668).

Research_area:Cardiovascular

Applications:ELISA

Target_protein:HMGCS1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.094ng/mL

Detection range:0.2-60ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:3-hydroxy-3-methylglutaryl-Coenzyme A Synthase 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P04035

MASS(Da):97,476

GeneID:3156

Synonyms:3-hydroxy-3-methylglutaryl-coenzyme A reductase;HMG-CoA reductase;HMGCS1;LDLCQ3

Gene names:HMGCR

Standard solution:64ng/mL