Human 26S Protease Regulatory Subunit 6B, PSMC4 ELISA Kit

SKU: E4873Hu

Size:96 Tests-1 Kit

Background:Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC4 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into Peptides.

Research_area:Others

Applications:ELISA

Target_protein:PSMC4

Reactivity:Human

Assay type:Sandwich

Sensitivity:7.45ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:26S Protease Regulatory Subunit 6B

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P43686

MASS(Da):47,366

GeneID:5704

Synonyms:26S proteasome AAA-ATPase subunit RPT3;26S proteasome regulatory subunit 6B;MB67-interacting protein;MIP224;Proteasome 26S subunit ATPase 4;PSMC 4;PSMC4;Tat-binding protein 7;TBP-7;

Gene names:PSMC4

Standard solution:3200ng/L