HSD11B1 Polyclonal Antibody

SKU: E-AB-52192

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: HSD11B1

Target Synonym: 11 beta HSD 1;11 beta HSD1;11 beta hydroxysteroid dehydrogenase 1;11 DH;11-beta hydroxysteroid dehydrogenase;type 1;11-beta-HSD1;11-beta-hydroxysteroid dehydrogenase 1;11-DH;11DH;Corticosteroid 11 beta dehydrogenase isozyme 1;Corticosteroid 11-beta-dehydrogenase isozyme 1;CORTRD2;DHI1;HDL;HSD 11;HSD11;HSD11B;HSD11B1;HSD11L;Hydroxysteroid (11 beta) dehydrogenase;Hydroxysteroid (11 beta) dehydrogenase 1;MGC13539;SDR26C1;short chain dehydrogenase/reductase family 26C;member 1

Research Areas: Cancer;Metabolism;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P28845

Accession:

Background: The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.

Concentration: 1.2 mg/mL

Immunogen: Fusion protein of human HSD11B1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: IHC 1:50-1:200

Calculated MW:

ObservedMW: