HORMAD1 Antibody - Cat. #: CSB-PA803140LA01HU

SKU: CSB-PA803140LA01HU

Size :50ug

Clone Number:

Aliases:HORMAD1 antibody; NOHMA antibody; HORMA domain-containing protein 1 antibody; Cancer/testis antigen 46 antibody; CT46 antibody; Newborn ovary HORMA protein antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q86X24

Immunogen:Recombinant Human HORMA domain-containing protein 1 protein (201-394AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:HORMAD1

Research Areas:Cancer; Immunology