HOPX antibody , Cat. # FNab03970

SKU: FNab03970

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase(HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy(By similarity). May act as a tumor suppressor.

Immunogen:HOP homeobox

Synonyms:HOD, HOP, LAGY, NECC1, OB1

Observed MW:8-12kd

Uniprot ID:Q9BPY8

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, IF, WB

Recommended dilution:WB: 1:500-1:2000; IF: 1:50-1:200

Gene ID:84525

Research Area:Cardiovascular, Metabolism, Developmental biology