HLA-DQB2 Polyclonal Antibody

SKU: E-AB-53101

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:HLA-DQB2

Target Synonym:DV19.1 (major histocompatibility complex; class II; DQ beta 2 (HLA-DXB));DX-beta;HLA class II histocompatibility antigen; DQ beta 2 chain;HLA class II histocompatibility antigen; DX beta chain;HLA DQB1;HLA DXB;major histocompatibility complex; class II; DQ beta 1;Major histocompatibility complex; class II; DQ beta 2;Major histocompatibility complex; class II; DX beta;MHC class II antigen DQB2

Research Areas:Immunology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P05538

Accession:

Background:HLA-DQB2 belongs to the family of HLA class II beta chain paralogs. Class II molecules are heterodimers consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. They play a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). Polymorphisms in the alpha and beta chains specify the peptide binding specificity, and typing for these polymorphisms is routinely done for bone marrow transplantation. However this gene, HLA-DQB2, is not routinely typed, as it is not thought to have an effect on transplantation. There is conflicting evidence in the literature and public sequence databases for the protein-coding capacity of HLA-DQB2. Because there is evidence of transcription and an intact ORF, HLA-DQB2 is represented in Entrez Gene and in RefSeq as a protein-coding locus.

Concentration:1.26 mg/mL

Immunogen:Fusion protein of human HLA-DQB2

Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method:Antigen affinity purification

Dilution:IHC 1:50-1:200

Calculated MW:

ObservedMW: