Histone deacetylase 7a Polyclonal Antibody

SKU: BT-AP03987

Size:100μL

Background:Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase 7 encoded by HDAC7 has sequence homology to members of the histone deacetylase family. HDAC7 is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research_area:Epigenetics and Nuclear Signaling

Target_protein:HDAC7

applications:WB, IHC-p, ELISA

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Histone deacetylase 7a Antibody

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):102927

UniProt accession:Human: Q8WUI4; Mouse: Q8C2B3

Synonyms:HDAC7; HDAC7A; Histone deacetylase 7; HD7; Histone deacetylase 7A; HD7a

GeneID:Human: 51564; Mouse: 56233