HECW1 Antibody - Cat. #: CSB-PA748484HA01HU

SKU: CSB-PA748484HA01HU

Size :50ul

Clone Number:

Aliases:C2 and WW domain-containing protein 1 antibody; E3 ubiquitin-protein ligase HECW1 antibody; HECT antibody; HECT type E3 ubiquitin ligase antibody; HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 antibody; HECT, C2 and WW domain-containing protein 1 antibody; HECW 1 antibody; Hecw1 antibody; HECW1_HUMAN antibody; hNEDL1 antibody; NEDD4 like ubiquitin protein ligase 1 antibody; NEDD4-like E3 ubiquitin-protein ligase 1 antibody; NEDL1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q76N89

Immunogen:Recombinant Human E3 ubiquitin-protein ligase HECW1 protein (751-900AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IF; Recommended dilution: IF:1:50-1:200

Background:E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Antigen Affinity purified & Affinity purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:HECW1

Research Areas:Signal Transduction