HASP Polyclonal Antibody

SKU: BT-AP09817

Size:100μL

Background:Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,Required for normal alignment of chromosomes at metaphase. Phosphorylates histone H3 'Thr-3' during mitosis.,PTM:Autophosphorylated on both serine and threonine residues (By similarity). Phosphorylated during mitosis. Phosphorylated upon DNA damage, probably by ATM or ATR.,Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Haspin subfamily.,Contains 1 protein kinase domain.,tissue specificity:Strongly expressed in testis. Also present in thymus and bone marrow and low levels observed in prostate, intestine, lung, spleen and lymph node. Expressed in fetal skin, liver, kidney and small intestine and also in proliferating but not non-proliferating cell lines.,

Research_area:Epigenetics and nuclear signaling

Target_protein:GSG2

applications:WB, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Serine/threonine-protein kinase haspin

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q8TF76; Mouse: Q9Z0R0

Synonyms:Serine/threonine-protein kinase haspin ;EC 2.7.11.1;Germ cell-specific gene 2 protein;H-haspin;Haploid germ cell-specific nuclear protein kinase

GeneID:Human: 83903