HAMP Antibody - Cat. #: CSB-PA010124KA01HU

SKU: CSB-PA010124KA01HU

Size :100ul

Clone Number:

Aliases:Hamp antibody; HEPC antibody; HEPC_HUMAN antibody; Hepc20 antibody; Hepc25 antibody; HEPCIDIN antibody; Hepcidin 20 antibody; Hepcidin 25 antibody; Hepcidin antimicrobial peptide antibody; Hepcidin-20 antibody; Hepcidin25 antibody; HFE2 antibody; HFE2B antibody; LEAP 1 antibody; LEAP-1 antibody; LEAP1 antibody; Liver expressed antimicrobial peptide antibody; Liver-expressed antimicrobial peptide 1 antibody; PLTR antibody; Putative liver tumor regressor antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P81172

Immunogen:Recombinant protein of Human HAMP

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; WB:1:500-1:2000, IHC:1:50-1:200

Background:The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Affinity purification

Conjugate:Non-conjugated

Buffer:Store at -20°C or -80°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:HAMP

Research Areas:Cancer?Cardiovascular;Metabolism;Signal transduction