H2B2E Rabbit Polyclonal Antibody

SKU: BT-AP10339

Size:100μL

Background:Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A| H2B| H3| and H4) form an octamer| around which approximately 146 bp of DNA is wrapped in repeating units| called nucleosomes. The linker histone| H1| interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family| and generates two transcripts through the use of the conserved stem-loop termination motif| and the polyA addition motif. The protein has antibacterial and antifungal antimicrobial activity.

Research_area:Epigenetics and nuclear signaling

Target_protein:HIST2H2BE

applications:WB

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:H2B2E

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):13860

UniProt accession:Human: Q16778; Mouse: Q64524

Synonyms:H2B2E

GeneID:Human: 8349; Mouse: 319189