GSK3B antibody , Cat. # FNab03674

SKU: FNab03674

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Glycogen synthase kinase-3(GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase .GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation.In skeletal muscle, it contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. Researches showed that the crystal structure of human GSK3B, expressed in insect cells, at 2.8-angstrom resolution .This antibody recognize the C-terminal of GSK3B.

Immunogen:glycogen synthase kinase 3 beta

Synonyms:GSK 3 beta, GSK3 beta, GSK3A B, GSK3B, GSK-3B, GSK3B 216P, gsk3beta

Observed MW:50 kDa

Uniprot ID:P49841

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IF, IHC, IP

Recommended dilution:WB: 1:500-1:2000; IP: 1:500-1:2000; IHC: 1:100-1:400; IF: 1:20-1:200

Gene ID:2932

Research Area:Signal Transduction, Metabolism, Cardiovascular, Immunology, Developmental biology, Neuroscience, Cell Division and Proliferation