GRPR Polyclonal Antibody

SKU: E-AB-12444

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: GRPR

Target Synonym: BB2;Bombesin BB2 receptor;bombesin receptor 2;Gastrin Releasing Peptide Receptor;Gastrin-releasing peptide receptor;GRP preferring bombesin receptor;GRP R;GRP-preferring bombesin receptor;GRP-R;Grp/bombesin receptor;Grpr;GRPR

Research Areas: Cancer;Neuroscience;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P30550

Accession:

Background: Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.

Concentration: 1.1 mg/mL

Immunogen: Synthetic peptide of human GRPR

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:200-1:1000;IHC 1:50-1:200

Calculated MW: 43kDa

ObservedMW: