GRIA3 Monoclonal Antibody

SKU: BT-MCA3557

Size:100μL

Background:Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.

Research_area:Signal transduction, Neuroscience

Target_protein:GRIA3

applications:IHC

Reactivity:Human

Clonality:Monoclonal

Clone ID:1D2

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:GRIA3

Immunogen:Purified recombinant fragment of human GRIA3 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):101kDa

UniProt accession:P42263

Synonyms:GLUR3, GLURC, GluA3, MRX94, GLUR-C, GLUR-K3

GeneID:2892