GPR75 Antibody - Cat. #: CSB-PA009829LA01HU

SKU: CSB-PA009829LA01HU

Size :50ug

Clone Number:

Aliases:G protein coupled receptor 75 antibody; GPR chr2 antibody; Gpr75 antibody; GPR75_HUMAN antibody; GPRchr2 antibody; OTTHUMP00000159608 antibody; Probable G protein coupled receptor 75 antibody; Probable G-protein coupled receptor 75 antibody; WI 31133 antibody; WI31133 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O95800

Immunogen:Recombinant Human Probable G-protein coupled receptor 75 protein (372-540AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200

Background:G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:GPR75

Research Areas:Signal transduction