GOT1 antibody , Cat. # FNab09876

SKU: FNab09876

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-mercaptopyruvate sulfurtransferase(3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.

Immunogen:glutamic-oxaloacetic transaminase 1, soluble(aspartate aminotransferase 1)

Synonyms:AATC, CAT, GIG18, GOT1, Transaminase A

Observed MW:43-46 kDa

Uniprot ID:P17174

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, IHC, IF, WB

Recommended dilution:WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:10-1:100

Gene ID:2805

Research Area:Neuroscience, Metabolism