GLRA2 antibody , Cat. # FNab03487

SKU: FNab03487

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine(PubMed:2155780, PubMed:15302677, PubMed:16144831, PubMed:23895467, PubMed:25445488). Channel opening is also triggered by taurine and beta-alanine(PubMed:15302677). Plays a role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents(PubMed:25445488). Plays a role in cellular responses to ethanol(PubMed:23895467).

Immunogen:glycine receptor, alpha 2

Synonyms:GLR, GLRA2, glycine receptor, alpha 2

Observed MW:48 kDa

Uniprot ID:P23416

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IHC

Recommended dilution:WB: 1:500-1:1000; IHC: 1:20-1:200

Gene ID:2742

Research Area:Neuroscience, Signal Transduction, Developmental biology