GJB6 Polyclonal Antibody

SKU: E-AB-15680

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: GJB6

Target Synonym: Connexin 30;Connexin-30;Cx30;CXB6;DFNA3;DFNA3B;DFNB1B;ECTD2;ectodermal dysplasia 2;hidrotic (Clouston syndrome);ED2;EDH;Gap junction beta 6 protein;Gap junction beta-6 protein;gap junction protein;beta 6 (connexin 30);gap junction protein;beta 6;Gap junction protein;beta 6;30kDa;GJB6;HED;HED2;NSRD1

Research Areas: Neuroscience;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: O95452

Accession:

Background: Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel. In the past, connexin protein names were based on their molecular weight, however the new nomenclature uses sequential numbers based on which form (alpha or beta) of the gap junction is present. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in some families with hidrotic ectodermal dysplasia.

Concentration: 0.4 mg/mL

Immunogen: Synthetic peptide of human GJB6

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: IHC 1:25-1:100

Calculated MW:

ObservedMW: