GFAP Mouse mAb

SKU: EM1059

Size: 100μL

Source:Mouse

Applications:WB, IHC

Reactivity:Rat, Mouse

Dilution:WB 1:2,000-5,000 IHC 1:200-500

Immunogen:Synthetic Peptide

Storage_stability:PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality:Monoclonal

Isotype:IgG1

Concentration:1mg/mL

Observed_band(KD):45kDa

Human_gene_id:2670

Human_swiss_prot_no:P14136

Subcellular_location:Cytoplasm. Associated with intermediate filaments

Other_name:Glial Fibrillary Acidic Protein ;Intermediate Filament Protein

Background:GFAP is a member of the class III intermediate filament protein family. It is heavily, and specifically, expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non myelinating Schwann cells in peripheral nerves. In addition, neural stem cells frequently strongly express GFAP. Antibodies to GFAP are therefore very useful as markers of astrocytic cells. In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes.