GBA Polyclonal Antibody

SKU: E-AB-19899

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: GBA

Target Synonym: Acid beta glucosidase;Acid beta-glucosidase;Alglucerase;Beta glucocerebrosidase;BETA GLUCOSIDASE; ACID;Beta-glucocerebrosidase;betaGC;D glucosyl N acylsphingosine glucohydrolase;D-glucosyl-N-acylsphingosine glucohydrolase;EC 3.2.1.45 ;GBA;Gba protein ;GBA1;GC;GCase;GCB;GLCM;GLUC;Glucocerebrosidase (alt.) ;Glucocerebrosidase;GLUCOCEREBROSIDASE PSEUDOGENE;Glucosidase beta;Glucosidase; beta; acid;Glucosidase; beta; acid (includes glucosylceramidase);Glucosylceramidase;Imiglucerase;Lysosomal glucocerebrosidase ;OTTHUMP00000033992;OTTHUMP00000033993

Research Areas: Cancer;Metabolism;Neuroscience;Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P04062

Accession:

Background: This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.

Concentration: 1.56 mg/mL

Immunogen: Synthetic peptide of human GBA

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:500-1:2000;IHC 1:50-1:100

Calculated MW: 60 kDa

ObservedMW: Refer to figures