GAPDH Monoclonal Antibody

SKU: BT-MCA4853

Size:100μL

Background:Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. It catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The enzyme exists as a tetramer of identical chains. Besides its functioning as a glycolytic enzyme in cytoplasm, recent evidence suggest that mammalian GAPDH is also involved in a great number of intracellular proceses such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. During the last decade a lot of findings appeared concerning the role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death, age- related neuronal diseases, such as Alzheimer

Research_area:Others

Target_protein:GAPDH

applications:WB, IHC, ICC

Reactivity:Human, Mouse, Rat

Clonality:Monoclonal

Clone ID:1A10

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:GAPDH

Immunogen:Purified recombinant fragment of human GAPDH expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):37kDa

UniProt accession:P04406

Synonyms:G3PD, GAPD, MGC88685

GeneID:2597