FRS2 antibody , Cat. # FNab03225

SKU: FNab03225

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.

Immunogen:fibroblast growth factor receptor substrate 2

Synonyms:FGFR signaling adaptor SNT, FGFR substrate 2, FRS2, FRS2A, FRS2alpha, SNT, SNT 1, SNT1

Observed MW:60 kDa

Uniprot ID:Q8WU20

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, IHC, WB, IF

Recommended dilution:WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:10-1:100

Gene ID:10818

Research Area:Signal Transduction