FOXK1 Polyclonal Antibody

SKU: E-AB-19286

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: FOXK1

Target Synonym: A630048H08Rik;AI463295;ENSMUSG00000075577;FHX;Fork head;Forkhead box protein K1;FOXJ2 forkhead factor;FOXK1;FOXK1;Gm10868;MNF;Myocyte nuclear factor

Research Areas: Cancer;Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: WB

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P85037

Accession:

Background: The FOX family of transcription factors share a common DIUA binding domain termed a winged-helix or forkhead domain. Many FOX proteins play important roles in development, metabolism, cancer and aging. In skeletal muscles, undifferentiated myogenic stem cells (satellite cells) can mobilize to regenerate myofibers in response to injury. FOXK1 is expressed in these cells and regulates cell cycle progression through an interaction with its downstream target the cyclin-dependent kinase inhibitor p21 (CIP). Loss of FOXK1 in mice results in growth retardation and a severe impairment in skeletal muscle regeneration following injury. FOXK1 also shows expression in immature tissues of brain, eye, heart, lung and thymus. It also is predominantly expressed in many malignant tissues, such as tumors of the brain, colon and lymph node.

Concentration: 1.5 mg/mL

Immunogen: Synthetic peptide of human FOXK1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 75 kDa

ObservedMW: Refer to figures