FMR1 Monoclonal Antibody

SKU: BT-MCA4721

Size:100μL

Background:FMR1, also known as POF, FMRP, FRAXA. Entrez Protein: NP_002015. It is an RNA-binding protein that associates with polyribosomes and is a likely component of a messenger ribonuclear protein (mRNP) particle The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs.

Research_area:Others

Target_protein:FMR1

applications:IHC, ICC

Reactivity:Human

Clonality:Monoclonal

Clone ID:4G9

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:FMR1

Immunogen:Purified recombinant fragment of human FMR1 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):71kDa

UniProt accession:Q06787

Synonyms:POF, FMRP, POF1, FRAXA

GeneID:2332