Fibronectin antibody , Cat. # FNab10458

SKU: FNab10458

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Fibronectin 1(FN1) is a high molecular weight glycoprotein which exists in both a soluble form in plasma(plasma FN1) and other body fluids and an insoluble form in the extracellular matrix(cellular FN1). Plasma FN1(dimeric form) is secreted by hepatocytes. Cellular FN(dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. FN1 binds to cell surfaces through integrins and to various compounds including collagen, fibrin and heparin. It is involved in cell adhesion and migration processes including embryogenesis, wound healing, hemostasis, host defense, and metastasis.(PMID: 7276612; 12244123; 12847088)

Immunogen:fibronectin 1

Synonyms:CIG, Cold insoluble globulin, DKFZp686F10164, DKFZp686H0342, DKFZp686I1370, DKFZp686O13149, ED B, Fibronectin, fibronectin 1, FINC, FN, FN1, FNZ, GFND, GFND2, LETS, MSF

Observed MW:220-270 kDa

Uniprot ID:P02751

Reactivity:Human

Tested Application:ELISA, WB, IHC

Recommended dilution:WB: 1:200-1:2000; IHC: 1:50-1:200

Gene ID:2335

Research Area:Stem Cells, Cancer, Signal Transduction