FGG Monoclonal Antibody

SKU: BT-MCA4199

Size:100μL

Background:The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.

Research_area:Cardiovascular

Target_protein:FGG

applications:IHC, ICC, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:4H9

Host:Mouse

Isotype:Mouse IgG2a

Gene Symbol/ Name:FGG

Immunogen:Purified recombinant fragment of human FGG expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):52kDa

UniProt accession:P02679

Synonyms:FGG

GeneID:2266