FCGR3A Monoclonal Antibody,PE Conjugated - Cat. #: CSB-MA279768

SKU: CSB-MA279768

Size :100ul

Clone Number:

Aliases:

Product Type:Monoclonal Antibody

Immunogen Species:Human

UniProt ID:P08637

Immunogen:Recombinant Protein

Raised in:Mouse

Species Reactivity:Human

Tested Applications:ELISA,IF,FC;Recommended dilution:IF:1:100-1:200

Background:COC16 reacts with human CD16, a 50-65 kDa Fcg receptor IIIa (FcgRIII), expressed on NK cells, monocytes/macrophages and granulocytes. It is a human NK cell associated antigen. CD16 is a low affinity receptor for IgG which functions in phagocytosis and ADCC, as well as in signal transduction and NK cell activation. The CD16 antibody blocks the binding of soluble immune complexes to granulocytes.This clone is cross reactive with non-human primate.1. Knapp, W.,et al. (1989) Leucocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, New York.2. Stroncek, D.F., et al. (1991) Blood 77:1572.3. Wirthmueller, U., et al. (1992) J. Exp. Med. 175:1381.4. Barclay, N.A., et al. (1993) The Leucocyte Antigen FactBook, CD16 section, Academic Press Inc.,San Diego, Calfornia, p. 136.

Clonality:Monoclonal

Isotype:IgG1

Purification Method:Affinity purified

Conjugate:Non-conjugated

Buffer:Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:FCGR3A

Research Areas:Immunology;Stem cells