FBXL4 Rabbit Polyclonal Antibody

SKU: BT-AP10010

Size:100μL

Background:This gene encodes a member of the F-box protein family| which are characterized by an approximately 40 amino acid motif| the F-box. F-box proteins constitute one subunit of modular E3 ubiquitin ligase complexes| called SCF complexes| which function in phosphorylation-dependent ubiquitination. The F-box domain mediates protein-protein interactions and binds directly to S-phase kinase-associated protein 1. In addition to an F-box domain| the encoded protein contains at least 9 tandem leucine-rich repeats. The ubiquitin ligase complex containing the encoded protein may function in cell-cycle control by regulating levels of lysine-specific demethylase 4A. Alternative splicing results in multiple transcript variants.

Research_area:Epigenetics and nuclear signaling

Target_protein:FBXL4

applications:WB

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:FBXL4

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):68310

UniProt accession:Human: Q9UKA2; Mouse: Q8BH70

Synonyms:FBXL4

GeneID:Human: 26235; Mouse: 269514