FBN1 Antibody - Cat. #: CSB-PA142599

SKU: CSB-PA142599

Size :100ul

Clone Number:

Aliases:350 kDa glycoprotein component extracellular microfibril antibody; ACMICD antibody; FBN 1 antibody; FBN antibody; FBN1 antibody; FBN1_HUMAN antibody; Fibrillin 15 antibody; Fibrillin-1 antibody; Fibrillin1 antibody; Fibrillin15 antibody; GPHYSD2 antibody; Marfan syndrome antibody; MASS antibody; MFS 1 antibody; MFS1 antibody; OCTD antibody; SGS antibody; SSKS antibody; Weill Marchesani syndrome antibody; WMS antibody; WMS2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P35555

Immunogen:Synthesized peptide derived from Human Fibrillin-1.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; IHC:1:50-1:100

Background:Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-1-containing microfibrils provide long-term force bearing structural support. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively.

Ehab El-Hallous, J. Biol. Chem., Mar 2007; 282: 8935 - 8946.
Shazia S. Chaudhry, J. Cell Biol., Jan 2007; 176: 355 - 367.
Kerstin Tiedemann, J. Biol. Chem., Sep 2001; 276: 36035 - 36042.
Liliana Schaefer, Am. J. Pathol., Aug 2004; 165: 383 - 396.

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:FBN1

Research Areas:Signal transduction